Cialis is a medication that has been approved for two specific conditions, which are erectile dysfunction in men (ED) and benign prostatic hyperplasia (BPH). However, Cialis is also frequently used to relieve the excessive constriction of the blood vessels in the lungs in patients who suffer from pulmonary hypertension, which allows them to exercise without experience shortness of breath and extreme fatigue.
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About Cialis: active component
Cialis contains the active drug that is called Tadalafil, which is a unique type of phosphodiesterase type 5 (PDE5) blocker or inhibitor in the sense that, unlike other drugs from the same category like Sildenafil or Vardenafil, its effects last substantially longer. In fact, Tadalafil is also known as “the weekend pill” among erectile dysfunction sufferers due to its ability to maintain its beneficial effects up to 36 hours. ED is a condition that affects numerous men around the globe, and it consists in the inability to maintain an adequate erectile response as a result of sexual stimulation, which makes sexual intercourse difficult and the sexual life problematic both physiologically and psychologically.
The female partners of ED sufferers also experience the consequences, which can create relationship problems and unwanted psychological issues. Benign prostatic hyperplasia (BPH) is basically the enlargement of the prostate tissue, which creates a compressive effect and makes urinary flow difficult and problematic. Cialis (Tadalafil) is frequently favored among other PDE5 inhibitors because it does not necessitate a frequent administration due to its prolonged period of effective action. However, the mechanism of action of Tadalafil is essentially the same as other representatives of the PDE5 blocker category, such as Avanafil, Sildenafil or Vardenafil.
How does Cialis influence the physiologic mechanisms that result in a restored ability to achieve strong erections in ED sufferers?
Sexual stimulation causes a flow of nervous impulses from the brain to the penis. The nerve endings will produce nitric oxide as a response, which is a messenger that carries the signal to specific enzymes that are activated. The activated enzymes produce cyclic GMP, which is a chemical that targets the blood vessels in the corpus cavernosum of the penis, which are specialized structures that can greatly dilate through filling with huge amounts of blood. They are also known as the cavernous bodies. The dilation caused by sufficient amounts of cyclic GMP causes the cavernous bodies to become filled with large amounts of blood as a result of strong and sustained blood vessel dilation in the penis. However, the PDE5 enzyme destroys cyclic GMP, and thus ends its erection-causing effects. By blocking the PDE5, Cialis is able to sustain sufficient amounts of cGMP for an adequate erection in response to sexual stimulation. Discuss your intention to use Cialis for your erectile problems with your physician.
I am General practitioner (GP) in Melbourne since 2006.