Tadalafil (Cialis) is a medication that is employed in the treatment of erectile dysfunction, but also as a therapy for pulmonary hypertension in certain cases. Tadalafil is included in the class of drugs that are called phosphodiesterase type 5 inhibitors, which is a biologically active enzyme that is involved in erection and blood vessel constriction in the lungs.
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Alternative to Cialis
Also included in this category are drugs like Viagra (Sildenafil) and Kamagra, which have almost the same mechanism of action as Tadalafil with small differences. Tadalafil can help a man who suffers from erectile dysfunction by facilitating the dilation of blood vessels in the cavernous bodies in the penis, which improves the sexual performance.
How Cialis works
The erection occurs when a man is sexually aroused, which causes nerve endings in the penis to release nitric oxide (NO) as a signaling molecule. NO activates certain receptors, which leads to the formation of cGMP, which is the active compound that directly influences the blood vessels in the penis to dilate, and therefore more blood will enter in the cavernous bodies causing an erection. This mechanism is deficient in men who have erectile dysfunction. Tadalafil can help such patients by inhibiting PDE5, which is the enzyme that destroys cGMP thus ending its action. The end result is that more cGMP will become available and the blood vessels in the penis will dilate more effectively, leading to a better erection and sexual performance. Tadalafil is also used to treat pulmonary arterial hypertension because of its unique ability to dilate the blood vessels in the lungs, which causes relief of symptoms.
Safety first
“Although Tadalafil is an effective remedy for erectile dysfunction or pulmonary hypertension, it is best to consult a medical professional before considering treatment with this drug. Tadalafil is different from the drugs of the same category such as Sildenafil and Vardenafil because it has a longer life in the human body, which means that it has a prolonged action and is eliminated slower from the body.”
John Hopkins, M.D.
Generic Cialis
Generic Cialis is cheaper than brand one. It is a main difference. Generic pill contain same amount of Tadalafil (10mg or 20mg) but can have other shape and color. The duration of Cialis action is about 36 hours, which is why it is frequently named “the weekend pill”.
Possible side effects
Tadalafil should be taken only when needed for erectile dysfunction rather than as a continuous therapy. Although generally Cialis is a safe medication, certain side effects that are usually mild or temporary may occur. They may include flushing, headache, abdominal discomfort or digestive disturbances, nasal congestion and nausea. Other more serious side effects are very rare, but you should report to your doctor any unpleasant occurrences that take place during treatment with Tadalafil to ensure that you get the most benefits.
Alternative to Cialis is Kamagra.
I am General practitioner (GP) in Melbourne since 2006.