Levitra (Vardenafil 20mg) has been tested and approved in Australia as a solid remedy in the treatment of erectile dysfunction in men. As with other PDE5 inhibitors, like Cialis, Viagra or Stendra, levitra may be used off label for other medical indications.
Levitra efficacy
For example, some PDE5 inhibitors are effective in reducing the symptoms of pulmonary hypertension. Vardenafil also has demonstrated its effectiveness in the treatment of premature ejaculation due to its capacity to prolong the time between vaginal penetration and ejaculation. Vardenafil works on an enzyme level in the cavernous structures of the penis where certain physiologic deficiencies may be responsible for the bothersome symptoms of erectile dysfunction. Basically, all PDE5 inhibitors work in a similar manner, including Vardenafil, but your doctor should choose the appropriate remedy based on his or her evaluation of absorption times, duration effects and interaction with other drugs that you may have been recommended for certain ailments.
How does Levitra influence the male physiology to eliminate the symptoms of ED and restore the normal erectile response to sexual stimulation?
Levitra and the other representatives of the PDE5 inhibitor group work by blocking the action of a specialized enzyme entitled the phosphodiesterase type 5, which is mostly located in the penis, but may also be present in the lung tissue. Sexual arousal is followed by a signal transmitted from the brain to the nerve endings in the penis, which results in the release of nitric oxide (NO) as a messenger chemical that carries the sexual stimulation to the blood vessels. NO influences certain enzymes to produce cGMP, which is the main chemical that acts on the smooth muscles of the blood vessels, causing their relaxation, being followed by an immense blood entry into the cavernous bodies of the penis. This is the mechanism of a normal erection in response to sexual arousal experienced by a man. However, PDE5 is there to destroy cGMP, and terminate the erectile response. This enzyme may work excessively in men who are unable to achieve a normal erection, or the production of cGMP may be too slow. Either way, Vardenafil is able to inhibit the PDE5, which normally leads to increased levels of cGMP and a strong blood vessel response that results in a solid erection and a dramatically improved sexual life. Vardenafil is active for about 4-5 hours after oral intake.
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Typical side effects
Side effects are minor, but may include nausea, headaches, muscle pain, nasal congestion or skin rash. It is important to inform your doctor about the intention to take Vardenafil to relieve the symptoms of erectile dysfunction, especially if you are also taking other medications for some medical disorders that you have been diagnosed with.
I am General practitioner (GP) in Melbourne since 2006.